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Article

Role of the htrA gene in Klebsiella pneumoniae virulence.

Infection and immunity - 1 Sept 2002

Cortés Guadalupe, de Astorza Beatriz, Benedí Vicente J, Albertí Sebastián

Abstract excerpt

We recently described the use of mini-Tn5 to generate complement-sensitive mutants derived from a complement-resistant Klebsiella pneumoniae clinical isolate deficient in the lipopolysaccharide O side chain. One mutant with a reduced capacity to survive in nonimmune human sera carried the transposon inserted in the htrA gene. We cloned and sequenced the gene and predicted from the deduced amino acid sequence that...

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Identifiers

PMID: 12183518
DOI: 10.1128/IAI.70.9.4772-4776.2002
PMCID: PMC128236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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