Article
Molecular genetic characterization of XRCC4 function.
International immunology - 1 Oct 1997
Mizuta R, Cheng H L, Gao Y, Alt F W
Abstract excerpt
XRCC4 is a generally expressed protein of 334 amino acids that is involved in the repair of DNA double-strand breaks and in V(D)J recombination, but its function is unknown. In this study, we have used a mutational approach and the yeast two-hybrid method to perform an initial characterization of this protein. We show that the XRCC4 protein is located in the nucleus. We also demonstrate that several potential...
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