Article
Beta-thalassaemia in indigenous Belgians: an update.
Acta clinica Belgica - 1 Jan 1997
Irenge L M, Derclaye I, Heusterspreute M, Gala J L, Philippe M
Abstract excerpt
Beta-thalassaemia, a widespread autosomal recessive disorder, occurs sporadically in Northern and Western European countries. Molecular analysis of the beta-globin gene has been carried out in 30 members of 15 unrelated indigenous Belgian families which presented with non sideropenic hypochromic...
Topics
- Adenine
- Amino Acid Substitution
- Anemia
- Anemia, Hypochromic
- Belgium
- Beta-Globulins
- Blotting, Southern
- Codon
- Cystine
- Gene Deletion
- Guanine
- Heterozygote
- Humans
- Immunoblotting
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Risk Factors