Article
Beta-thalassemia in Yugoslavia.
Hemoglobin - 1 Jan 1990
Dimovski A, Efremov D G, Jankovic L, Juricic D, Zisovski N, Stojanovski N, Nikolov N, Petkov G T, Reese A L, Stoming T A
Abstract excerpt
This study concerned the evaluation of beta-thalassemia alleles in nearly 50 patients with beta-thalassemia major and in 130 -thalassemia heterozygotes using gene amplification and dot-blot hybridization with synthetic probes. Fourteen different mutations were observed; of these, three (IVS-I-110...
Topics
- Alleles
- Base Sequence
- DNA Mutational Analysis
- Gene Frequency
- Genes
- Genotype
- Globins
- Hemoglobinopathies
- Hemoglobins, Abnormal
- Humans
- Thalassemia
- Yugoslavia