Article
Mediterranean types of beta-thalassemia in the German population.
Human genetics - 1 Jun 1990
Laig M, Pape M, Hundrieser J, Flatz G
Abstract excerpt
Forty beta-thalassemia genes from unrelated German heterozygotes with no known foreign ancestry were examined using the oligonucleotide technique and DNA restriction analysis, with the aim of determining the contribution of Mediterranean beta-thalassemia mutations to the prevalence of this trait in the German population. Of the 40 beta-thalassemia genes, 26 were identified as Mediterranean types (20 beta 39...
Topics
- DNA
- DNA Restriction Enzymes
- Germany, West
- Heterozygote
- Humans
- Mutation
- Oligonucleotide Probes
- Prevalence
- Thalassemia
