Article
A new mutation in the beta-globin gene (IVS II-850 G-C) found in a Yugoslavian beta-thalassemia heterozygote.
Haematologica - 1 Jan 2000
Jankovic L, Dimovski A J, Sukarova E, Juricic D, Efremov G D
Abstract excerpt
BACKGROUND: The recent development of laboratory techniques that can rapidly characterize the molecular defects of beta-thalassemia has resulted in the discovery of more than 100 different point mutations in the beta-globin gene. These mutations are population specific. About 20 of them account f...
Topics
- Base Sequence
- Blotting, Northern
- Globins
- Heterozygote
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA Splicing
- Thalassemia
- Yugoslavia