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Article

Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins.

Neuron - 1 Jun 1995

Curtis R, Adryan K M, Stark J L, Park J S, Compton D L, Weskamp G, Huber L J, Chao M V, Jaenisch R, Lee K F

Abstract excerpt

The receptor mechanisms mediating the retrograde axonal transport of the neurotrophins have been investigated in adult rats. We show that transport of the TrkB ligands NT-4 and BDNF to peripheral neurons is dependent on the low affinity neurotrophin receptor (LNR). Pharmacological manipulation of LNR in vivo using either an anti-LNR antibody or a soluble recombinant LNR extracellular domain completely blocked...

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Source

Identifiers

PMID: 7541633
DOI: 10.1016/0896-6273(95)90267-8

Genes

BDNF
NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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