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Article

Heat shock-induced excessive relaxation of DNA in Escherichia coli mutants lacking the histone-like protein HU.

Biochimica et biophysica acta - 12 Sept 1997

Ogata Y, Inoue R, Mizushima T, Kano Y, Miki T, Sekimizu K

Abstract excerpt

Plasmid DNA in exponentially growing Escherichia coli immediately relaxes after heat shock but the relaxed DNA re-supercoils rapidly, the despite continued presence of the heat shock conditions. We have now obtained genetic evidence indicating that the histone-like protein HU of E. coli is required for this re-supercoiling of DNA. Plasmid DNA in a hupA-hupB double gene-disruption mutant relaxed excessively after...

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Source

Identifiers

PMID: 9349725
DOI: 10.1016/s0167-4781(97)00105-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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