Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of Escherichia coli histone-like protein HU in DNA replication: HU-beta suppresses the thermosensitivity of dnaA46ts.

Biochimie - 1 Feb 2001

Bahloul A, Boubrik F, Rouviere-Yaniv J

Abstract excerpt

The HU protein is a small, basic, heat-stable DNA-binding protein that is well-conserved in prokaryotes and is associated with the bacterial nucleoid. In enterobacteria, including Escherichia coli, HU is a heterotypic dimer, HUalphabeta, composed of two closely related sub-units encoded by the hupA and hupB genes, respectively. HU was shown to participate in vitro in the initiation of DNA replication as an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cephalosporins
Share to Chromosomes, Bacterial
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme Inhibitors

Share to Escherichia coli Proteins

Share to Flow Cytometry

Share to Hot Temperature

Share to Rifampin

Source

Identifiers

PMID: 11278072
DOI: 10.1016/s0300-9084(01)01246-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of Escherichia coli histone-like protein HU in DNA replication: HU-beta suppresses the thermosensitivity of dnaA46ts.PMID 11278072Read ↗

Coordination of genomic structure and transcription by the main bacterial nucleoid-associated protein HU.Semantic proximity Read ↗

Increased sensitivity to gamma irradiation in bacteria lacking protein HU.Semantic proximity Read ↗

Histone-like protein HU and bacterial DNA topology: suppression of an HU deficiency by gyrase mutations.Semantic proximity Read ↗

Right-handed DNA supercoiling by an octameric form of histone-like protein HU: modulation of cellular transcription.Semantic proximity Read ↗

Heat shock-induced excessive relaxation of DNA in Escherichia coli mutants lacking the histone-like protein HU.Semantic proximity Read ↗

The HU regulon is composed of genes responding to anaerobiosis, acid stress, high osmolarity and SOS induction.Semantic proximity Read ↗

Escherichia coli HU protein suppresses DNA-gyrase-mediated illegitimate recombination and SOS induction.Semantic proximity Read ↗

Escherichia coli HU protein has a role in the repair of abasic sites in DNA.Semantic proximity Read ↗

Subunit-specific phenotypes of Salmonella typhimurium HU mutants.Semantic proximity Read ↗

Requirement of integration host factor (IHF) for growth of Escherichia coli deficient in HU protein.Semantic proximity Read ↗

The Escherichia coli histone-like protein HU has a role in stationary phase adaptive mutation.Semantic proximity Read ↗

Expression of the seqA gene is negatively modulated by the HU protein in Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.