Exclusion of five trinucleotide repeat (CAG and CCG) expansions in 17 families with schizophrenia.

doi:10.1016/s0006-3223(97)00011-5

Back to search

Article

Exclusion of five trinucleotide repeat (CAG and CCG) expansions in 17 families with schizophrenia.

Biological psychiatry - 1 Nov 1997

Ohara K, Tani K, Tsukamoto T, Suzuki Y, Xu H D, Xu D S, Wang Z C, Ohara K

Abstract excerpt

Trinucleotide repeat expansion diseases are characterized by anticipation. Several studies suggested the anticipation in schizophrenia. We studied five novel trinucleotide repeats identified by Li et al in a human brain cDNA library in 100 unrelated control subjects, and 57 subjects in 17 familie...

Topics

Adolescent
Adult
Aged
Alleles
DNA, Complementary
Female
Gene Frequency
Gene Library
Humans
Male
Middle Aged
Polymorphism, Genetic
Risk Factors
Schizophrenia
Trinucleotide Repeats

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.