Article
Three CAG trinucleotide repeats on chromosome 6 (D6S1014, D6S1015, and D6S1058) are not expanded in 30 families with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 1997
Ohara K, Tani K, Tsukamoto T, Ino A, Nagai M, Suzuki Y, Xu H D, Xu D S, Wang Z C, Ohara K
Abstract excerpt
Since 1991, more than five neuro-genetic disorders have been recognized to be caused by trinucleotide repeat expansions, and the list of such disease should grow. The diseases are characterized clinically by the phenomenon of anticipation, i.e., worsening of the disease phenotype in successive generations with increasing trinucleotide repeat expansion. The presence of anticipation in familial schizophrenia has...
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