Article
A CAG trinucleotide repeat expansion and familial schizophrenia.
Psychiatry research - 17 Jul 2000
Ohara1 K, Ikeuchi T, Suzuki Y, Ohtani M, Ohara K, Tsuji S
Abstract excerpt
Studies which showed anticipation in families with schizophrenia suggested that a trinucleotide repeat expansion mechanism may be involved in the pathogenesis of familial schizophrenia. Furthermore, some studies involving the repeat expansion detection (RED) method showed the median length of CAG repeats to be longer in probands with schizophrenia than that in control subjects. We screened for a possible expanded...
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