Article
Tumor necrosis factor promoter gene polymorphism associated with increased susceptibility to non-Hodgkin's lymphomas.
European journal of haematology - 1 Feb 2007
Bel Hadj Jrad Besma, Chatti Amel, Laatiri Adnene, Ahmed Slim Ben, Romdhane Abdelaziz, Ajimi Salem, Chouchane Lotfi
Abstract excerpt
The tumor necrosis factor (TNF) is a pro-inflammatory cytokine involved in the severity of different immune-regulated diseases including autoimmune, infectious, and malignant diseases. Chronic immune system stimulation could be a potential etiologic factor in these diseases. Given the determining role of TNF acting early in the immune response, we investigated the effect of an inherited genetic polymorphism at...
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