Article
Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer.
International journal of cancer - 15 Apr 2010
Partida-Rodríguez Oswaldo, Torres Javier, Flores-Luna Lourdes, Camorlinga Margarita, Nieves-Ramírez Miriam, Lazcano Eduardo, Perez-Rodríguez Martha
Abstract excerpt
Tumour Necrosis Factor (TNF) and Heat Shock Protein 70 (HSP70) are important molecules in inflammatory, infectious and tumoral processes. The genes codifying these molecules are polymorphic and certain alleles have been associated with susceptibility to disease. Gastric cancer is associated with an Helicobacter pylori-induced chronic inflammatory response. The aim of this work was to analyze whether polymorphisms...
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