Article
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Circulation - 16 Sept 1997
Nordestgaard B G, Abildgaard S, Wittrup H H, Steffensen R, Jensen G, Tybjaerg-Hansen A
Abstract excerpt
BACKGROUND: Patients with mutations on both alleles of the lipoprotein lipase gene resulting in complete lipoprotein lipase deficiency exhibit the chylomicronemia syndrome with severe hypertriglyceridemia and increased risk of pancreatitis and possibly of ischemic heart disease. This study examined frequency, lipid levels, and risk of ischemic heart disease for heterozygous carriers of lipoprotein lipase...
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