Article
Hypertriglyceridaemia due to genetic defects in lipoprotein lipase and apolipoprotein C-II.
Journal of internal medicine - 1 Jun 1992
Fojo S S, Brewer H B
Abstract excerpt
Hypertriglyceridaemia, as defined by fasting triglyceride levels of greater than 2.8 mmol l-1, is a prevalent dyslipoproteinaemia in our population. The underlying pathophysiological mechanisms that result in elevations of plasma triglycerides are heterogeneous and, in most cases, incompletely understood. However, in a subset of patients presenting with this lipid disorder, the biochemical and genetic defects...
Topics
- Apolipoprotein C-II
- Apolipoproteins C
- Genes, Recessive
- Humans
- Hyperlipoproteinemia Type I
- Lipoprotein Lipase
- Mutation
- Pancreatitis
- Pedigree