Article
SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.
Molecular and cellular biology - 1 Oct 1997
Sumi-Ichinose C, Ichinose H, Metzger D, Chambon P
Abstract excerpt
The yeast and animal SNF-SWI and related multiprotein complexes are thought to play an important role in processes, such as transcription factor binding to regulatory elements, which require nucleosome remodeling in order to relieve the repressing effect of packaging DNA in chromatin. There are two mammalian homologs of the yeast SNF2-SWI2 subunit protein, SNF2alpha-brm and SNF2beta-BRG1, and overexpression of...
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