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Article

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.

Development (Cambridge, England) - 1 Jun 2016

He Shuying, Limi Saima, McGreal Rebecca S, Xie Qing, Brennan Lisa A, Kantorow Wanda Lee, Kokavec Juraj, Majumdar Romit, Hou Harry, Edelmann Winfried, Liu Wei, Ashery-Padan Ruth, Zavadil Jiri, Kantorow Marc, Skoultchi Arthur I, Stopka Tomas, Cvekl Ales

Abstract excerpt

Ocular lens morphogenesis is a model for investigating mechanisms of cellular differentiation, spatial and temporal gene expression control, and chromatin regulation. Brg1 (Smarca4) and Snf2h (Smarca5) are catalytic subunits of distinct ATP-dependent chromatin remodeling complexes implicated in transcriptional regulation. Previous studies have shown that Brg1 regulates both lens fiber cell differentiation and...

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Identifiers

PMID: 27246713
DOI: 10.1242/dev.135285
PMCID: PMC4920164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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