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Article

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

The Journal of biological chemistry - 10 Apr 2009

Flowers Stephen, Nagl Norman G, Beck George R, Moran Elizabeth

Abstract excerpt

The mammalian SWI/SNF chromatin-remodeling complex is essential for the multiple changes in gene expression that occur during differentiation. However, the basis within the complex for specificity in effecting positive versus negative changes in gene expression has only begun to be elucidated. The catalytic core of the complex can be either of two closely related ATPases, BRM or BRG1, with the potential that the...

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Identifiers

PMID: 19144648
DOI: 10.1074/jbc.M808782200
PMCID: PMC2665061

Genes

HDAC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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