Article
Role of steroidogenic-factor 1 in basal and 3',5'-cyclic adenosine monophosphate-mediated regulation of cytochrome P450 side-chain cleavage enzyme in the mouse.
Biology of reproduction - 1 Oct 1997
Chau Y M, Crawford P A, Woodson K G, Polish J A, Olson L M, Sadovsky Y
Abstract excerpt
The orphan receptor steroidogenic factor-1 (SF-1) plays a major role in adrenal and gonadal development and sexual differentiation, and it has been shown to interact with shared promotor elements to increase the expression of cytochrome P450 side-chain cleavage (P450scc) and other steroid hydroxylases in vitro. We took a step-wise approach to define the role of SF-1 in regulation of hormone-induced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
