Article
Steroidogenic factor 1 (SF-1) and SP1 are required for regulation of bovine CYP11A gene expression in bovine luteal cells and adrenal Y1 cells.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 1997
Liu Z, Simpson E R
Abstract excerpt
Cholesterol side-chain cleavage cytochrome P450 (CYP11A; P450scc) gene expression is regulated by gonadotropins via cAMP in the ovary and by ACTH via cAMP in adrenal cortical cells. Previously, we have characterized a response element located at -118 to -101 bp in the 5'-flanking region of the bo...
Topics
- Adrenal Gland Neoplasms
- Animals
- Base Sequence
- Binding Sites
- COS Cells
- Cattle
- Cells, Cultured
- Cholesterol Side-Chain Cleavage Enzyme
- Corpus Luteum
- Cyclic AMP
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Female
- Fushi Tarazu Transcription Factors
- Gene Expression Regulation
- Genes, Reporter
- Homeodomain Proteins
- Luciferases
