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Article

Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25.

American journal of human genetics - 1 Aug 1997

McIndoe R A, Stanford J L, Gibbs M, Jarvik G P, Brandzel S, Neal C L, Li S, Gammack J T, Gay A A, Goode E L, Hood L, Ostrander E A

Abstract excerpt

Linkage of a putative prostate cancer-susceptibility locus (HPC1) to chromosome 1q24-25 has recently been reported. Confirmation of this linkage in independent data sets is essential because of the complex nature of this disease. Here we report the results of a linkage analysis using 10 polymorphic markers spanning approximately 37 cM in the region of the putative HPC1 locus in 49 high-risk prostate cancer...

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Identifiers

PMID: 9311739
DOI: 10.1086/514853
PMCID: PMC1715908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25.PMID 9311739Read ↗

Linkage analysis of 150 high-risk prostate cancer families at 1q24-25.Semantic proximity Read ↗

Linkage analysis of chromosome 1q markers in 136 prostate cancer families. The Cancer Research Campaign/British Prostate Group U.K. Familial Prostate Cancer Study Collaborators.Semantic proximity Read ↗

Combined analysis of hereditary prostate cancer linkage to 1q24-25: results from 772 hereditary prostate cancer families from the International Consortium for Prostate Cancer Genetics.Semantic proximity Read ↗

In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer.Semantic proximity Read ↗

Prostate cancer susceptibility locus HPC1 in Utah high-risk pedigrees.Semantic proximity Read ↗

Linkage of prostate cancer susceptibility loci to chromosome 1.Semantic proximity Read ↗

Linkage analyses at the chromosome 1 loci 1q24-25 (HPC1), 1q42.2-43 (PCAP), and 1p36 (CAPB) in families with hereditary prostate cancer.Semantic proximity Read ↗

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Confirmation of prostate cancer susceptibility genes using high-risk families.Semantic proximity Read ↗

Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.Semantic proximity Read ↗

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