Article
Linkage analysis of 150 high-risk prostate cancer families at 1q24-25.
Genetic epidemiology - 1 Mar 2000
Goode E L, Stanford J L, Chakrabarti L, Gibbs M, Kolb S, McIndoe R A, Buckley V A, Schuster E F, Neal C L, Miller E L, Brandzel S, Hood L, Ostrander E A, Jarvik G P
Abstract excerpt
Confirmation of linkage and estimation of the proportion of families who are linked in large independent datasets is essential to understanding the significance of cancer susceptibility genes. We report here on an analysis of 150 high-risk prostate cancer families (2,176 individuals) for potential linkage to the HPC1 prostate cancer susceptibility locus at 1q24-25. This dataset includes 640 affected men with an...
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