Article
Developmental analysis of bone tumors in polyomavirus transgenic mice.
Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1994
Wang R, Siegal G P, Scott D L, Bautch V L
Abstract excerpt
BACKGROUND: Transgenic mice carrying the polyoma (Py) early region gene develop both vascular and bone tumors that express the transgene (R. Wang and V. L. Bautch, J. Virol. 65:5174-5183, 1991). To determine the correlation between bone tumor formation and transgene expression, mice of two lines that showed differences in tumor pattern were analyzed. EXPERIMENTAL DESIGN: Py DNA encoding the early region gene was...
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