Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glycyl-glutamine in nucleus accumbens reduces ethanol intake in alcohol preferring (P) rats.

Brain research - 5 Oct 2005

Resch Garth E, Shridharani Shyam, Millington William R, Garris David R, Simpson C Wayne

Abstract excerpt

Opioid peptides and glycyl-glutamine (Gly-Gln) have been implicated in the control of ethanol consumption. A recognized beta-endorphin cleavage product, Gly-Gln, inhibits voluntary alcohol consumption when microinjected into the nucleus accumbens (AcbSh) of P rats. To evaluate the site-specific efficacy of Gly-Gln on ethanol consumption following AcbSh application, ethanol preferring (P) rats were allowed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Central Nervous System Depressants

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dipeptides

Share to Ethanol

Share to Narcotic Antagonists

Share to Nucleus Accumbens

Share to Rats, Mutant Strains

Share to Receptors, Opioid

Source

Identifiers

PMID: 16212948
DOI: 10.1016/j.brainres.2005.07.066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glycyl-glutamine in nucleus accumbens reduces ethanol intake in alcohol preferring (P) rats.PMID 16212948Read ↗

Further characterization of the GlyT-1 inhibitor Org25935: anti-alcohol, neurobehavioral, and gene expression effects.Semantic proximity Read ↗

Glycine receptors containing α2 or α3 subunits regulate specific ethanol-mediated behaviors.Semantic proximity Read ↗

Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical InvestigationsSemantic proximity Read ↗

Spontaneous and ethanol-stimulated in vitro release of beta-endorphin by the hypothalamus of AA and ANA rats.Semantic proximity Read ↗

Effects of melanocortin receptor activation and blockade on ethanol intake: a possible role for the melanocortin-4 receptor.Semantic proximity Read ↗

Advances in the use of naltrexone: an integration of preclinical and clinical findings.Semantic proximity Read ↗

Deficit in beta-endorphin peptide and tendency to alcohol abuse.Semantic proximity Read ↗

Drosophila GABA(B) receptors are involved in behavioral effects of gamma-hydroxybutyric acid (GHB).Semantic proximity Read ↗

Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking rat.Semantic proximity Read ↗

6-OHDA-lesions of the nucleus accumbens disrupt the acquisition but not the maintenance of ethanol consumption in the alcohol-preferring P line of rats.Semantic proximity Read ↗

Operant self-administration of ethanol in C57BL/6 mice lacking beta-endorphin and enkephalin.Semantic proximity Read ↗

Stimulated dopamine overflow and alpha-synuclein expression in the nucleus accumbens core distinguish rats bred for differential ethanol preference.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.