Article
Determinants of acquired activated protein C resistance and D-dimer in breast cancer.
Thrombosis research - 1 Sept 2016
Tinholt Mari, Sandset Per Morten, Mowinckel Marie-Christine, Garred Øystein, Sahlberg Kristine Kleivi, Kristensen Vessela N, Børresen-Dale Anne-Lise, Jacobsen Anne Flem, Skretting Grethe, Iversen Nina
Abstract excerpt
BACKGROUND: We have previously reported acquired activated protein C (APC) resistance and elevated plasma D-dimer levels in breast cancer patients. Here, we aimed to identify phenotypic and genetic determinants that contribute to the acquired APC resistance and increased D-dimer levels in breast cancer. Healthy controls served as reference. We also addressed whether higher APC resistance or D-dimer levels could...
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