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Article

Studies in a large family with late-onset Alzheimer disease (LOAD).

Alzheimer disease and associated disorders - 1 Sept 1997

Martin E S, Martin S E, Edelsohn L, Borgaonkar D S

Abstract excerpt

A large 10-generation family with late-onset Alzheimer disease (LOAD) inherited as an autosomal dominant trait was evaluated historically, clinically, and genetically. The family origin was traced to a founder couple of French ancestry with approximately 3,000 descendants. Although the transmission of a genetic predisposition to LOAD is demonstrated through male individuals, a predominance of affected women is...

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Identifiers

PMID: 9305502
DOI: 10.1097/00002093-199709000-00009

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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