Article
Early-onset Alzheimer disease in families with late-onset Alzheimer disease: a potential important subtype of familial Alzheimer disease.
Archives of neurology - 1 Sept 2006
Brickell Kiri L, Steinbart Ellen J, Rumbaugh Malia, Payami Haydeh, Schellenberg Gerard D, Van Deerlin Vivianna, Yuan Wuxing, Bird Thomas D
Abstract excerpt
BACKGROUND: Genetic influences on the development of late-onset Alzheimer disease (LOAD) are heterogeneous and ill defined. OBJECTIVE: To determine the genetic risk factors for LOAD. DESIGN: We asked the following questions: (1) Does early-onset Alzheimer disease (EOAD) occur in families with predominantly LOAD? and (2) Does the apolipoprotein E (APOE) genotype explain the wide differences in onset age in LOAD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.