Article
Decreased cognitive function in extended family members from the single late-onset-Alzheimer's-disease pedigree.
Journal of the International Neuropsychological Society : JINS - 1 Aug 2013
Zeng Yan, Chang Wei, Shu Chang, Ma Lina, Huang Yuanyuan, Wang Ruoshi, Zhang Junpeng, Zhu Changcai, McClintock Shawn M
Abstract excerpt
A family history of dementia is associated with an increased risk of developing Alzheimer's disease (AD) late in life (LOAD). This study marked the first attempt to assess the familial contribution to differences in cognitive performance in a large family-based group in the Chinese community. We enrolled 168 participants without dementia from a single pedigree with 9 probable AD patients diagnosed after age 65....
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