Gene targeting for inflammatory cell adhesion molecules.

doi:10.1007/978-3-0348-7343-7_13

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Article

Gene targeting for inflammatory cell adhesion molecules.

Agents and actions. Supplements - 1 Jan 1995

Bullard D C, Sandberg E T, Scharffetter-Kochanek K, Beaudet A L

Abstract excerpt

Using gene targeting in mouse embryonic stem cells, it is possible to introduce diverse mutations into specific genes. Using these methods, various laboratories have reported mutations for a variety of inflammatory cell adhesion molecules including CD18, alpha 5 integrin, ICAM-1, P-selectin, and...

Topics

Animals
Cell Adhesion Molecules
Gene Targeting
Inflammation
Integrins
L-Selectin
Mutation
P-Selectin
Platelet Membrane Glycoproteins

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