Genotyping of the polymorphic N-acetyltransferase (NAT2) and loss of heterozygosity in bladder cancer patients.

doi:10.1111/j.1399-0004.1998.tb02753.x

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Article

Genotyping of the polymorphic N-acetyltransferase (NAT2) and loss of heterozygosity in bladder cancer patients.

Clinical genetics - 1 May 1998

Schnakenberg E, Ehlers C, Feyerabend W, Werdin R, Hübotter R, Dreikorn K, Schloot W

Abstract excerpt

Acetylation is one of the major routes in metabolism and detoxification of a large number of drugs, chemicals and carcinogens. Slow acetylators are said to be more susceptible to developing bladder cancer and because of investigations about tumor risk based on phenotyping procedures, it was our aim to study the distribution of allelic constellations of the N-acetyltransferase (NAT2) by genotyping patients with...

Topics

Acetylation
Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Arylamine N-Acetyltransferase
Female
Gene Frequency
Genotype
Humans
Loss of Heterozygosity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Sex Factors

Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9660060
DOI: 10.1111/j.1399-0004.1998.tb02753.x

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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