[Estrogen receptors and breast cancer].

Article

[Estrogen receptors and breast cancer].

La Revue du praticien - 15 May 1994

Maudelonde T, Pujol P, Rochefort H

Abstract excerpt

Activation of oestrogen receptor has a promoting effect in early steps of mammary carcinogenesis. Loss of oestrogen receptor, or of its functionality is associated to more aggressive and hormone unresponsive breast cancers. Anti-oestrogens are antiproliferative agents inhibiting oestrogens and gr...

Topics

Breast Neoplasms
Chromosomes, Human, Pair 6
Estrogen Antagonists
Female
Genetic Variation
Humans
Mutation
Receptors, Estrogen

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