Article
[Estrogen receptors and breast cancer].
La Revue du praticien - 15 May 1994
Maudelonde T, Pujol P, Rochefort H
Abstract excerpt
Activation of oestrogen receptor has a promoting effect in early steps of mammary carcinogenesis. Loss of oestrogen receptor, or of its functionality is associated to more aggressive and hormone unresponsive breast cancers. Anti-oestrogens are antiproliferative agents inhibiting oestrogens and growth factors action by binding to the oestrogen receptor. Assay of oestrogen and progesterone receptors, in the cytosol...
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