Mutations in the estrogen receptor gene.

doi:10.1002/humu.1380060202

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Article

Mutations in the estrogen receptor gene.

Human mutation - 1 Jan 1995

Sluyser M

Abstract excerpt

Somatically generated mutations in the estrogen receptor (ER) have been found at the mRNA/cDNA level in human breast cancer biopsies and in established breast cancer cell lines. Aberrantly spliced ER mRNA causes the appearance of truncated or internally deleted ER protein forms. Studies on the fu...

Topics

Breast Neoplasms
Chromosome Mapping
Female
Humans
Meningeal Neoplasms
Meningioma
Mutation
Receptors, Estrogen

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