Article
Oestrogen receptor variants and mutations in human breast cancer.
Annals of medicine - 1 Jun 1997
Murphy L C, Leygue E, Dotzlaw H, Douglas D, Coutts A, Watson P H
Abstract excerpt
Several oestrogen receptor variant and mutated mRNA species have been identified in human breast samples and cell lines. Over-expression and altered expression of some of these mRNAs have been correlated with breast tumourigenesis and progression. The following review focuses on the current knowl...
Topics
- Animals
- Breast Neoplasms
- Cell Line
- Chromosome Deletion
- Exons
- Female
- Humans
- Mutation
- Point Mutation
- RNA, Messenger
- Receptors, Estrogen