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Article

Cross-linking hybridization assay for direct detection of factor V Leiden mutation.

Clinical chemistry - 1 Sept 1997

Zehnder J, Van Atta R, Jones C, Sussman H, Wood M

Abstract excerpt

A nucleic acid photocross-linking technology was used in the development of a direct assay for factor V Leiden, a point mutation in the factor V gene (G1691A) that is the most common inherited risk factor for thrombosis. This cross-linking hybridization assay included two allele-specific capture...

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PMID: 9299963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9299963-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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