Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A whole-blood homogeneous assay for the multiplex detection of the factor V G1691A and the prothrombin G20210A mutations.

Molecular and cellular probes - 1 Aug 2005

Hobson-Peters Jody, Toye Philip

Abstract excerpt

We describe an assay for the simultaneous detection in DNA or whole blood samples of the G1691A (Leiden) mutation in the factor V allele and the G20210A mutation in the prothrombin allele, both of which predispose humans to thrombosis. The assay uses a dual-probe quenching system in which one probe of a pair is labelled with a fluorophore and the adjacent probe is labelled with a fluorescence quencher. The primer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Chemical Analysis
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor V

Share to Genotype

Share to Heterozygote

Share to Polymerase Chain Reaction

Share to Prothrombin

Source

Identifiers

PMID: 16006096
DOI: 10.1016/j.mcp.2005.04.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A whole-blood homogeneous assay for the multiplex detection of the factor V G1691A and the prothrombin G20210A mutations.PMID 16006096Read ↗

Rapid genotyping of factor V Leiden mutation using single-tube bidirectional allele-specific amplification and automated ultrathin-layer agarose gel electrophoresis.Semantic proximity Read ↗

A method for homogeneous color-compensated genotyping of factor V (G1691A) and methylenetetrahydrofolate reductase (C677T) mutations using real-time multiplex fluorescence PCR.Semantic proximity Read ↗

Testing for Factor V Leiden (FVL) and Prothrombin G20210A Genetic Variants.Semantic proximity Read ↗

Combined factor V leiden (G1691A) and prothrombin (G20210A) genotyping by multiplex real-time polymerase chain reaction using fluorescent resonance energy transfer hybridization probes on the Rotor-Gene 2000.Semantic proximity Read ↗

DNA technology for the detection of common genetic variants that predispose to thrombophilia.Semantic proximity Read ↗

Single-nucleotide polymorphism genotyping by melting analysis of dual-labeled probes: examples using factor V Leiden and prothrombin 20210A mutations.Semantic proximity Read ↗

Simultaneous determination of methylenetetrahydrofolate reductase C677T and factor V G1691A genotypes by mutagenically separated PCR and multiple-injection capillary electrophoresis.Semantic proximity Read ↗

Rapid automated simultaneous screening of (G1691A) Factor V, (G20210A) prothrombin, and (C677T) methylenetetrahydrofolate reductase variants by multiplex PCR using fluorescence scanning technology.Semantic proximity Read ↗

Τwo-panel molecular testing for genetic predisposition for thrombosis using multi-allele visual biosensors.Semantic proximity Read ↗

HyBeacon probes for rapid DNA sequence detection and allele discrimination.Semantic proximity Read ↗

Multiplex PCR for the detection of the factor V Leiden and prothrombin 20210A mutations.Semantic proximity Read ↗

Evaluation of the GeneXpert assay in the detection of Factor V Leiden and prothrombin 20210 in stored, previously classified samples.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.