Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of a new Rho family member in cell migration and axon guidance in C. elegans.

Cell - 5 Sept 1997

Zipkin I D, Kindt R M, Kenyon C J

Abstract excerpt

Rho family GTPases are thought to regulate actin-dependent processes, but their functions in vivo are still poorly understood. We have investigated the function of a new, widely expressed Rho family member in C. elegans by analyzing mutations in the endogenous gene. Activated and null alleles all inhibit cell migration, demonstrating that this protein is required for cell migration in vivo. Only a small subset of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Membrane
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Molecular Sequence Data

Share to Mutation

Share to Neurons

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 9298900
DOI: 10.1016/s0092-8674(00)80353-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of a new Rho family member in cell migration and axon guidance in C. elegans.PMID 9298900Read ↗

Mutationally activated Rho GTPases in cancer.Semantic proximity Read ↗

The RhoGAP myosin 9/HUM-7 integrates membrane signals to modulate Rho/RHO-1 during embryonic morphogenesis in <i>C. elegans</i>Semantic proximity Read ↗

FGF-dependent, polarized SOS activity orchestrates directed migration of <i>C. elegans</i> muscle progenitors independently of canonical effectors <i>in vivo</i>Semantic proximity Read ↗

The RhoGAP HUM-7/Myo9 integrates signals to modulate RHO-1/RhoA during embryonic morphogenesis in Caenorhabditis elegansSemantic proximity Read ↗

Mutations affecting embryonic cell migrations in Caenorhabditis elegans.Semantic proximity Read ↗

A systematic RNA interference screen reveals a cell migration gene network in C. elegans.Semantic proximity Read ↗

Interactions of UNC-34 Enabled with Rac GTPases and the NIK kinase MIG-15 in Caenorhabditis elegans axon pathfinding and neuronal migration.Semantic proximity Read ↗

The Caenorhabditis elegans nonmuscle myosin genes nmy-1 and nmy-2 function as redundant components of the let-502/Rho-binding kinase and mel-11/myosin phosphatase pathway during embryonic morphogenesis.Semantic proximity Read ↗

Functions of the novel RhoGAP proteins RGA-3 and RGA-4 in the germ line and in the early embryo of C. elegans.Semantic proximity Read ↗

The Rho guanine exchange factor RHGF-2 acts through the Rho-binding kinase LET-502 to mediate embryonic elongation in C. elegans.Semantic proximity Read ↗

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets.Semantic proximity Read ↗

The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.