Article

The RhoGAP myosin 9/HUM-7 integrates membrane signals to modulate Rho/RHO-1 during embryonic morphogenesis in <i>C. elegans</i>

2018-05-17

Abstract excerpt

During embryonic morphogenesis, cells and tissues undergo dramatic movements under the control of F-actin regulators. Our studies of epidermal cell migrations in developing C. elegans embryos have identified multiple plasma membrane signals that regulate the Rac GTPase, thus regulating WAVE and Arp2/3 complexes, to promote branched F-actin formation and polarized enrichment. We describe here a pathway that acts i...

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Literature Corpus work: e4a8d4f7-c608-5d7d-b5b3-d99c74fa649c
DOI: 10.1101/325274

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