Article
Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.
The American journal of pathology - 1 Sept 1993
Hoorens A, Lemoine N R, McLellan E, Morohoshi T, Kamisawa T, Heitz P U, Stamm B, Rüschoff J, Wiedenmann B, Klöppel G
Abstract excerpt
In a series of 22 pancreatic acinar cell carcinomas, including two acinar cystadenocarcinomas, cellular differentiation was analyzed by immunocytochemistry and electron microscopy. In addition, overexpression of p53 protein and Ki-ras codon 12 mutation was studied. Four of the 20 noncystic acinar...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Biomarkers, Tumor
- Carcinoma
- Female
- Gene Expression
- Genes, ras
- Humans
- Immunohistochemistry
- Male
- Microscopy, Electron
- Middle Aged
- Molecular Sequence Data
- Mutation
- Pancreatic Neoplasms
- Tumor Suppressor Protein p53