Article
Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.
The American journal of pathology - 1 Sept 1993
Hoorens A, Lemoine N R, McLellan E, Morohoshi T, Kamisawa T, Heitz P U, Stamm B, Rüschoff J, Wiedenmann B, Klöppel G
Abstract excerpt
In a series of 22 pancreatic acinar cell carcinomas, including two acinar cystadenocarcinomas, cellular differentiation was analyzed by immunocytochemistry and electron microscopy. In addition, overexpression of p53 protein and Ki-ras codon 12 mutation was studied. Four of the 20 noncystic acinar cell carcinomas showed a pure acinar pattern, nine an acinar-solid, and seven a solid pattern. All tumors stained for...
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