Article
[Interaction of anti-TNF-alpha monoclonal antibodies E7H2 with mutant and hybrid proteins].
Bioorganicheskaia khimiia - 1 May 1997
Shingarova L N, Sagaĭdak L N, Berkova H P, Korobko V G
Abstract excerpt
A number of hybrid proteins containing amino acid sequences of human lymphotoxin and human and mouse tumor necrosis factors were obtained by means of genetic engineering. By using these proteins, an antigenic determinant in the molecule of human tumor necrosis factor for monoclonal antibodies E7H2 (MAb E7H2), previously developed against this factor was localized. It was demonstrated by Western blot analysis that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
