Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of an additional p53-responsive site in the human epidermal growth factor receptor gene promotor.

Oncogene - 28 Aug 1997

Sheikh M S, Carrier F, Johnson A C, Ogdon S E, Fornace A J

Abstract excerpt

Exogenously introduced wild-type and mutant p53 have recently been reported to enhance the human epidermal growth factor receptor (EGF-R) gene promoter activity in p53-deficient Saos2 osteosarcoma cells. A p53 binding site residing at position -265/-239 in the EGF-R proximal promoter has also bee...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Breast Neoplasms
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Promoter Regions, Genetic

Share to Sequence Deletion

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9285564
DOI: 10.1038/sj.onc.1201264

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9285564-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Identification of an additional p53-responsive site in the human epidermal growth factor receptor gene promotor.PMID 9285564Read ↗

Transcriptional Activation of the Human Epidermal Growth Factor Receptor Promoter by Human p53Semantic proximity Read ↗

The human p73 promoter: characterization and identification of functional E2F binding sites.Semantic proximity Read ↗

Cloning and characterization of murine p53 upstream sequences reveals additional positive transcriptional regulatory elements.Semantic proximity Read ↗

Wild-type human p53 activates the human epidermal growth factor receptor promoter.Semantic proximity Read ↗

Transcriptional regulatory and response mapping of the rat Ha-ras upstream sequence using primary mammary epithelial cells.Semantic proximity Read ↗

Identification of a p53 Response Element in the Promoter Region of the hMSH2 Gene Required for Expression in A2780 Ovarian Cancer CellsSemantic proximity Read ↗

Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids.Semantic proximity Read ↗

A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer.Semantic proximity Read ↗

A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce ApoptosisSemantic proximity Read ↗

The region 3' to the major transcriptional start site of the MDR1 downstream promoter mediates activation by a subset of mutant P53 proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.