Article
Plasminogen activator inhibitor-1 (PAI-1) content in platelets from healthy individuals genotyped for the 4G/5G polymorphism in the PAI-1 gene.
Scandinavian journal of clinical and laboratory investigation - 1 Aug 1997
Nordenhem A, Wiman B
Abstract excerpt
We have studied PAI-1 activity and antigen content in platelets and in plasma from 37 healthy individuals who were also genotyped for the 4G/5G polymorphism in the PAI-1 promoter region. The PAI-1 data obtained were compared with the vitronectin and the beta-thromboglobulin contents in platelets from the same individuals. A highly significant correlation between PAI-1 activity and PAI-antigen was obtained, both...
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