Article
Association between PAI-1 4G/5G genotype and residual thrombus in acute mesenteric venous thrombosis.
Molecular biology reports - 20 Sept 2024
Liu Bin, Feng Hai, Li Wenrui
Abstract excerpt
OBJECTIVE: Plasminogen activator inhibitor-1 (PAI-1) is the most important inhibitor of plasminogen activator. The functional 4G/5G polymorphism of the gene coding for PAI-1 may affect PAI-1 plasmatic activity, influencing the imbalance between coagulation and fibrinolysis cascades. In this study, we investigated the association between the PAI-1 4G/5G genotype and the development and residual thrombus of acute...
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