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Article

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila.

Development (Cambridge, England) - 1 Aug 1997

Haerry T E, Heslip T R, Marsh J L, O'Connor M B

Abstract excerpt

In vitro experiments suggest that glycosaminoglycans (GAGs) and the proteins to which they are attached (proteoglycans) are important for modulating growth factor signaling. However, in vivo evidence to support this view has been lacking, in part because mutations that disrupt the production of GAG polymers and the core proteins have not been available. Here we describe the identification and characterization of...

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Identifiers

PMID: 9272947
DOI: 10.1242/dev.124.16.3055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila.PMID 9272947Read ↗

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