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Article

A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA.

Science (New York, N.Y.) - 29 Aug 1997

Lodmell J S, Dahlberg A E

Abstract excerpt

Direct evidence is presented for a conformational switch in 16S ribosomal RNA (rRNA) that affects tRNA binding to the ribosome and decoding of messenger RNA (mRNA). These data support the hypothesis that dynamic changes in rRNA structure occur during translation. The switch involves two alternating base-paired arrangements apparently facilitated by ribosomal proteins S5 and S12, and produces significant changes...

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Source

Identifiers

PMID: 9271564
DOI: 10.1126/science.277.5330.1262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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