Article
Airway Responsiveness in Two Inbred Strains of Mouse Disparate in IgE and IL-4 Production
1 Aug 1997
Abstract excerpt
The mouse provides an excellent model for genetic studies of asthma, which is characterized by airway hyperexcitability and hyperreactivity. The former is a function of the properties of the membrane of the airway smooth muscle (ASM), whereas the latter is a function, albeit indirectly, of the mechanical properties of the muscle contractile apparatus. The very small size of the muscle has in the past hampered its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
