Article
Can we differentiate between airway and vascular smooth muscle?
Clinical and experimental pharmacology & physiology - 1 Nov 2004
Fernandes Darren J, McConville John F, Stewart Alastair G, Kalinichenko Vladimir, Solway Julian
Abstract excerpt
1. Airway smooth muscle (ASM) has recently been termed the 'frustrated' cell of the lung given that contraction of ASM has no proven useful physiological function in adults and yet is indelibly associated with pathological conditions by virtue of its unwanted airflow-limiting actions in asthma. In contrast, pulmonary vascular smooth muscle contraction plays an essential role in the control of blood flow through...
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