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Article

A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation.

PloS one - 1 Jan 2013

Paez-Cortez Jesus, Krishnan Ramaswamy, Arno Anneliese, Aven Linh, Ram-Mohan Sumati, Patel Kruti R, Lu Jining, King Oliver D, Ai Xingbin, Fine Alan

Abstract excerpt

Phenotypes of lung smooth muscle cells in health and disease are poorly characterized. This is due, in part, to a lack of methodologies that allow for the independent and direct isolation of bronchial smooth muscle cells (BSMCs) and vascular smooth muscle cells (VSMCs) from the lung. In this paper, we describe the development of a bi-fluorescent mouse that permits purification of these two cell populations by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24040256
DOI: 10.1371/journal.pone.0074469
PMCID: PMC3767675

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