Article
Bronchial responsiveness among inbred mouse strains. Role of airway smooth-muscle shortening velocity.
American journal of respiratory and critical care medicine - 1 Mar 2000
Duguet A, Biyah K, Minshall E, Gomes R, Wang C G, Taoudi-Benchekroun M, Bates J H, Eidelman D H
Abstract excerpt
To investigate the relationship between bronchial responsiveness and airway smooth-muscle (ASM) contractile properties, we studied inbred mice with known interstrain differences in airway responsiveness. Using oscillatory mechanics, we confirmed that A/J mice were hyperresponsive to methacholine (MCh) as compared with mice of the C3H/HeJ and C57BL/6J strains. Analysis of respiratory system resistance and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
