Article
Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models.
The European respiratory journal - 1 Aug 2008
Meurs H, Gosens R, Zaagsma J
Abstract excerpt
Airway hyperresponsiveness (AHR) is a hallmark clinical symptom of asthma. At least two components of AHR have been identified: 1) baseline AHR, which is persistent and presumably caused by airway remodelling due to chronic recurrent airway inflammation; and 2) acute and variable AHR, which is associated with an episodic increase in airway inflammation due to environmental factors such as allergen exposure....
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